Amidst the chaos of COVID-19 news and propaganda of what you can do to prevent and treat the virus, there have been reports that ibuprofen should not be used if you test positive for COVID-19. What is ibuprofen? Ibuprofen (Advil®, Motrin®) is an over-the-counter medicine from a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs).  Ibuprofen is